Regenerative Cell Therapy is the “Ferrari of Healing.” This therapy delivers regenerative cells directly to the injured site and healing starts at the time of injection. It is the best treatment for arthritic joint pain from cartilage loss.
Autologous regenerative cell injection therapy utilizes the patient's own bone marrow, fat or placenta tissues. All are rich sources of regenerative cells. These cells are collected, filtered, centrifuged and injected into the injured areas. This method, promises to be particularly advantageous in treating advanced arthritis, severely degenerated tendons, ligaments, cartilage, spinal discs and chronic fractures. Science is showing that the tissue regenerative potential of mesenchymal regenerative cells (MSRs) may be the most important weapon in offering patients with degenerative arthritis a real non-surgical solution to REBUILDING damaged tissue that were previously thought irreparable.
It is given together with Platelet Rich Plasma (PRP). A small amount of blood is taken from your veins in the elbow (like giving blood for lab work). The blood is then placed in a centrifuge which spins and automatically creates the PRP. The entire process takes 40 minutes and increases the concentration of platelets and growth factors to decrease inflammation and stimulate cell repair. PRP is injected into the damaged area with either the fat or bone marrow regenerative cells. Together this super regenerative cell “soup” stimulates repair in the tendon, ligament, joint, and cartilage, causing mild inflammation that triggers the healing cascade. As a result, new collagen begins to develop. As this collagen matures it begins to shrink and causes the tightening and strengthening of the tendons or ligaments of the damaged area.
Autologous regenerative cells can be harvested from the patient’s own fat tissue or from the bone marrow of the crest of the hip bone. During this procedure a small volume of the patient's bone marrow is extracted from their iliac crest near the base of the spine, then placed in a centrifuge and spun at a high rate of speed to separate the mesenchymal regenerative cells from other blood cells. The concentrated bone marrow is then injected with PRP into the targeted joint or tendon.
Fat regenerative cell is harvested by liposuction from the hip or lateral thighs. A total of 3 oz of fat is harvested, centrifuged, separated, and injected with Platelet Rich Plasma into the injured tissues. Typically the tissues that are targeted for stimulation to repair are articular cartilage, but can be soft tissues structures such as ligaments and tendons.
Another regenerative cell therapy is placenta/ amniotic tissue. Placenta derived stem cell comes from consenting donors and is processed at an FDA regulated lab. It is checked for all sorts of diseases prior to being accepted for use in others. Placenta /Amniotic stem cell injections offer the ability to heal damaged tissue naturally. The tissue regeneration and repair properties of the amniotic cell fluid are anti-inflammatory effect that relieves pain and contains natural growth factors that assist in healthy tissue growth. Moreover, the hyaluronic acid that is also in amniotic fluid is an important component of the joint fluid that helps cartilage growth. Amniotic fluid is also a great source of regenerative cells, found in a much higher concentration than the adult bone marrow. And just like when one uses their own stem cells, the use of amniotic fluid doesn’t cause rejection or allergic reaction when injected into a patient. The placenta tissue is mixed with PRP and injected to the treatment areas.
It is important to understand that regenerative cells by themselves are unable to repair the injured area. These cells have to be properly directed, and the platelets perform the intended function. In effect, regenerative cells are construction workers and the platelets are their supervisors. Once they are activated, these regenerative cells perform a variety of valuable functions. Apart from repairing damage to the injured areas, regenerative cells help damaged cells repair themselves and participate in the repairing process. Regenerative Cell Therapy is a repair process that takes at least 4 weeks to months to complete.
Generally, the repair process takes three months to complete, but in most cases improvement can be noticed by 2-4 weeks. About four to six weeks after the regenerative cell therapy, the patient receives a platelet rich plasma injection into the affected area. These injections enable the regenerative cells to continue growth and multiply into cartilage tissue. Your healing and pain free recovery time depend on what cells are used for your condition.
Dr. Truong will determine which regenerative cell therapy (bone, fat, placenta, PRP) is best for your condition. For moderate to severe arthritis, combination therapy of at least 3 or 4 tissues are used to treat your condition. Each treatment protocol is customized to your injury and recovery process.
There are various conditions that can affect the progress of regenerative cell therapy—some positively, others negatively. Patients undergoing regenerative cell therapy or platelet rich plasma treatments are advised to minimize intake of alcohol and tobacco, as consumption of these substances tends to impede the body’s ability to release stem cells. Conversely, some supplements increase the number of regenerative cells. These will be recommended to you by our office.